Glossary

Explanation of terms used by DrugBank

Carcinogenicity


Carcinogenicity refers to the ability of a substance to cause cancer. DrugBank automatically retrieves information from the admetSAR prediction tool, using a table format to display various predicted properties of a drug. This database predicts the absorption, distribution, metabolism, excretion, and toxicity of drugs (ADMET) 1. One prediction that admetSAR makes is whether a drug is a carcinogen or non-carcinogen. This information can be found in a drug entry on DrugBank under the "Predicted ADMET features" section.

References:

  1. Cheng F, Li W, Zhou Y, Shen J, Wu Z, Liu G, Lee PW, Tang Y: admetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties. J Chem Inf Model. 2012 Nov 26;52(11):3099-105. doi: 10.1021/ci300367a. Epub 2012 Nov 1. [PubMed:23092397]