Glossary

Explanation of terms used by DrugBank

Human Intestinal Absorption

Synonyms:
HIA

In DrugBank, the property human intestinal absorption refers to the process through which orally administered drugs are absorbed from the gastrointestinal system into the bloodstream of the human body.

The value and probability predicted for this property are determined using software developed by admetSAR 1. The predicted value can be either '+' or '-', and refers to whether the drug being discussed does or does not undergo intestinal absorption, respectively. Finally, the predicted probability is a numerical value between 0 and 1 that represents the percentage probability of the aforementioned predicted value.

References:

  1. Cheng F, Li W, Zhou Y, Shen J, Wu Z, Liu G, Lee PW, Tang Y: admetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties. J Chem Inf Model. 2012 Nov 26;52(11):3099-105. doi: 10.1021/ci300367a. Epub 2012 Nov 1. [PubMed:23092397]