Explanation of terms used by DrugBank

CYP450 2C9 inhibitor ADMET Feature Prediction

Cytochrome P450 2C9 inhibitor

In DrugBank, the property CYP450 2C9 inhibitor refers to a drug or chemical that is capable of binding to the CYP450 2C9 enzyme and acts to decrease or diminish the activity of the enzyme.

The value and probability predicted for this property are determined using software developed by admetSAR 1. The predicted value can be either 'Inhibitor' or 'Non-inhibitor' and refers to whether the drug being discussed is or is not a CYP450 2C9 inhibitor, respectively. Finally, the predicted probability is a numerical value between 0 and 1 that represents the percentage probability of the aforementioned predicted value.


  1. Cheng F, Li W, Zhou Y, Shen J, Wu Z, Liu G, Lee PW, Tang Y: admetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties. J Chem Inf Model. 2012 Nov 26;52(11):3099-105. doi: 10.1021/ci300367a. Epub 2012 Nov 1. [PubMed:23092397]